Features of gait are determined at multiple levels, from the selection of the gait itself (e.g. walk or run) through the specific parameters utilized (stride length, frequency, etc.) to the pattern of muscular excitation. The ultimate choices are neurally determined, but what is involved with that decision process? Human locomotion appears stereotyped not so much because the pattern is predetermined, but because these movement patterns are good solutions for providing movement utilizing the machinery available to the individual (the legs and (...) their requisite components). Under different circumstances the appropriate solution may differ broadly (different gait) or subtly (different parameters). Interpretation of the neural decision making process would benefit from understanding the influences that determine the selection of the appropriate solution in any set of circumstances, including that of normal conditions. In this review we survey an array of studies that point to energetic cost as a key input to the gait coordination system, and not just an outcome of the gait pattern implemented. We then use that information to rigorously define the construct proposed by Sparrow and Newell (1998) where the effects of environment, organism and task act as constraints determining the solution set available, and the coordination pattern is then implemented under a pressure for energetic economy. Environment is defined in terms of affordances based on the ecological psychology definition of the concept and organism is defined as classic morphology and physiology based capabilities. We rely on a novel conceptualization of task that recognizes that the task goal needs to be separated from the mechanisms that achieve the goal if the motivation behind the selection of the mechanism strategy is to be exposed and understood. This reformulation of the Sparrow and Newell construct is then linked to the proposed pressure for economy by considering it as an optimization problem, where the most readily selected gait strategy will be that which achieves the task goal at (or near) the energetic minimum. (shrink)

It was proposed that the data from Monte Carlo statistical investigations be subjected to analysis of variance methods rather than the conventional techniques of tabling, graphing, and inspecting the data. Two examples in which analysis of variance methods were applied to published Monte Carlo studies were presented. It was suggested that balanced factorial designs should be used whenever possible in Monte Carlo studies so that analysis of variance methods would be directly applicable. Finally, three advantages of analysis of variance methods (...) over conventional techniques were described and analysis of variance methods were contrasted with a possible alternative analytical method, multiple regression analysis. (shrink)

After expressing our gratitude to the commentators for their valuable analyses and assessments of Principles of Biomedical Ethics, we respond to several particular critiques raised by the commentators under the following rubrics: the compatibility of different sets of principles and rules; challenges to the principle of respect for autonomy; connecting principles to cases and resolving their conflicts; the value of and compatibility of virtues and principles; common morality theory; and moral status. We point to areas where we see common agreement (...) with our commentators and respond to their critical evaluations. (shrink)

Hirsch’s revision results from his attempt to think through the difficult question that underlies the whole essay: How does the movement of time and circumstance affect the stability of meaning? The first part of his answer is that the relation between original meaning and subsequent understanding or applications of that meaning is analogous to the relation between a concept and its extension. For example, if he reads Shakespeare’s sonnet 55 and applies it to his beloved, and one of us reads (...) it and applies it to his beloved, “that does not make the meaning of the sonnet different for us, assuming that we both understand that the text’s meaning is not limited to any particular exemplification but rather embraces many, many exemplifications” . That is, the sonnet has a status analogous to that of the concept “bicycle,” and the two applications have a status analogous to that of a three-speed and a ten-speed bicycle. Whereas Hirsch formerly considered such exemplifications part of a text’s significance, he now considers them part of its meaning. This revision indicates that for Hirsch meaning is not the product of a consciousness producing an intrinsic genre but of a consciousness communicating something broader and more general than an intrinsic genre—an intention-concept that can have numerous extensions or exemplifications, including many that the originating consciousness could not have anticipated. Formerly, Hirsch used intrinsic genre to describe that sense of the whole which governed the horizon of developing meaning and which, when the work was completed—when all the blanks were filled in—gave the work its specific determinate meaning. That is, determinacy of meaning was in large part a function of narrowing the class of implications; when the work was completed, the class of implications was restricted to those synonymous with expressed meaning. In short, in the old theory, meaning-intention is a “narrow,” not a broad “concept.” James L. Battersby, professor of English at Ohio State University, is the author of Rational Praise and Natural Lamentation: Johnson, Lycidas, and Principles of Criticism and Elder Olson: An Annotated Bibliography. He is currently at work on a study of the relationship between “thought” and structure in various genres. James Phelan is associate professor English at Ohio State University and the author of Worlds from Words: A Theory of language in Fiction. His work in progress concerns character and narrative progression. (shrink)

What processes underlie the formation of new memories? What determines their strength? Where are the changes underlying memory located? With contributions from leading experts, this book offers the most up-to-date attempts to answer these and many more critical questions.

Health, Disease, and Illness brings together a sterling list of classic and contemporary thinkers to examine the history, state, and future of ever-changing "concepts" in medicine.

Substantial discussion in the neuroethical literature has addressed the possibility that deep brain stimulation (DBS) and adaptive DBS (aDBS) could result in changes in personality, agency, and ide...

Evidence does not support the claim that observers universally recognize basic emotions from signals on the face. The percentage of observers who matched the face with the predicted emotion (matching score) is not universal, but varies with culture and language. Matching scores are also inflated by the commonly used methods: within-subject design; posed, exaggerated facial expressions (devoid of context); multiple examples of each type of expression; and a response format that funnels a variety of interpretations into one word specified by (...) the experimenter. Without these methodological aids, matching scores are modest and subject to various explanations. (shrink)

Menninghaus et al. pose two open-ended questions: To what extent do formal elements of art elicit negative affect, and do artists try to elicit this response in a theory-based or intuitive manner? For popular movies, we argue that the consideration of their construction is prior to the consideration of the experience that they evoke.

Gathers medical and legal documents, opinions from various perspectives, and a timeline of events in the Terri Shiavo case to provide a resource for examining the moral and ethical issues surrounding end-of-life decisions.

We examined the efficacy of including a research intermediary (RI) during the consent process in reducing participants' perceptions of coercion to enroll in a research study. Eighty-four drug court clients being recruited into an ongoing study were randomized to receive a standard informed consent process alone (standard condition) or with an RI (intermediary condition). Before obtaining consent, RIs met with clients individually to discuss remaining concerns. Findings provided preliminary evidence that RIs reduced client perceptions that their participation might influence how (...) clinical and judicial staff view them. This suggests that using RIs may improve participant autonomy in clinical studies. (shrink)

Three correctives can get researchers out of the trap of constructing unitary theories of “thinking”: (1) Strong inference methods largely avoid problems associated with universal prescriptive normativism; (2) theories must recognize that significant modularity of cognitive processes is antithetical to general accounts of thinking; and (3) consideration of the domain-specificity of rationality render many of the present article's issues moot.

This book brings together scholars from a variety of epistemological perspectives to explore the multiple ways in which sexuality does indeed matter in the arena of public education.

This paper describes an AFOSR-supported basic research program that focuses on developing a new framework for combining hard with soft data in order to improve space situational awareness. The goal is to provide, in an automatic and near real-time fashion, a ranking of possible threats to blue assets (assets trying to be protected) from red assets (assets with hostile intentions). The approach is based on Conceptual Spaces models, which combine features from traditional associative and symbolic cognitive models. While Conceptual Spaces (...) are revolutionary, they lack an underlying mathematical framework. Several such frameworks have attempted to represent Conceptual Spaces, but by far the most robust is the model developed by Holender. His model utilizes integer linear programming in order to obtain an overall similarity value between observations and concepts that support the formation of hypotheses. This paper will describe a method for building Conceptual Spaces models for threats that utilizes ontologies as a means to provide a clear semantic foundation for this inferencing process; in particular threat ontologies and space domain ontologies are developed and employed in this approach. A space situational awareness use-case is presented involving a kinetic kill scenario and results are shown to assess the performance of this fusion-based inferencing framework. (shrink)

Jansen and Wall suggest a new way of defending hard paternalism in clinical research. They argue that non-therapeutic research exposing people to more than minimal risk should be banned on egalitarian grounds: in preventing poor decision-makers from making bad decisions, we will promote equality of welfare. We argue that their proposal is flawed for four reasons.First, the idea of poor decision-makers is much more problematic than Jansen and Wall allow. Second, pace Jansen and Wall, it may be practicable for regulators (...) to uncover the values that a potential research participant holds when agreeing to enter a research project, so their claim that we must ban such research projects for all if we are to ban them for poor decision-makers looks to be unmotivated. Third, there seem to be cases where the liberty to enter the sort of research project Jansen and Wall discuss is morally weighty, and arguably should outweigh concerns of egalitarian distribution. Fourth, banning certain types of research, which seem on the face of it to offer an unfavourable risk-benefit ratio, would have unwelcome consequences for all clinical research, which Jansen and Wall do not recognize. (shrink)

Ecological communities around the world are under threat while a consensus theory of community structure remains elusive. In the last decade ecologists have struggled with two seemingly opposing theories: niche-based theory that explains diversity with species’ differences and the neutral theory of biodiversity that claims that much of the diversity we observe can be explained without explicitly invoking species’ differences. Although ecologists are increasingly attempting to reconcile these two theories, there is still much resistance against the neutral theory of biodiversity. (...) Here we argue that the dispute between the two theories is a classic example of the dichotomy between philosophical perspectives, realism and instrumentalism. Realism is associated with specific, small-scale and detailed explanations, whereas instrumentalism is linked to general, large-scale, but less precise accounts. Recognizing this will help ecologists get both niche-based and neutral theories in perspective as useful tools for understanding biodiversity patterns. (shrink)

This path-breaking book reconceptualizes our understanding of political tolerance as well as of its foundations.

Book reviewed in this article: Principles of Biomedical Ethics. By Tom L. Beauchamp and James F. Childress.

We propose an experimental method to study the possible emergence of sensemaking in artificial agents. This method involves analyzing the agent's behavior in a test bed environment that presents regularities in the possibilities of interaction afforded to the agent, while the agent has no presuppositions about the underlying functioning of the environment that explains such regularities. We propose a particular environment that permits such an experiment, called the Small Loop Problem. We argue that the agent's behavior demonstrates sensemaking if the (...) agent learns to exploit regularities of interaction to fulfill its self-motivation as if it understood (at least partially) the underlying functioning of the environment. As a corollary, we argue that sensemaking and self-motivation come together. We propose a new method to generate self-motivation in an artificial agent called interactional motivation. An interactionally motivated agent seeks to perform interactions with predefined positive values and avoid.. (shrink)

Robustness properties of three equality of variances tests, the jackknife procedure, the k-sample Box-Andersen test, and Levene’s z test, were investigated and compared in a Monte Carlo study employing small samples from underlying gamma distributions and gamma mixtures. Overall, the jackknife test yielded rejection proportions usually closer to nominal levels under departures from normality, but the Box-Andersen test performed relatively well when departures from normality were not extreme. Four recommendations regarding testing variances were offered.

We question the falsifiability of Tsuda's theory and emphasise the need for physiologically based, quantitative models of large scale cortical function that can be validated through experimental data. We outline such a model emphasising its verification through experimental data and possible avenues for testing Tsuda's predictions about nonlinearities in neural behaviour.